Stable. : A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. Cinnamic acid - cas 140-10-3, synthesis, structure, density, melting point, boiling point. Propriétés physiques . trans-cinnamic acid shows moderate inhibition on the rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1 and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY … Cinnamic acid, ethanol and temperature interaction on coumarate decarboxylase activity and the relative expression of the putative cd gene in D. bruxellensis CINNAMIC ACID U14A832J8D Overview Structure Names 25: Classification 2: Identifiers 12: Relationships 4: Metabolites 1: Active Moiety 1: Notes 3: Audit Info References 34: History 1: … LD The alkali salts are sol in water. - Find MSDS or SDS, a COA, data sheets and more information. Get all suppliers and price by the below link: Reference only. Service & Support. Incompatible with strong oxidizing agents. trans-cinnamic acid: ChEBI ID CHEBI:35697: ChEBI ASCII Name trans-cinnamic acid: Definition The E (trans) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. 1995 Jul 28;62(3):345-50. Solide cristallin, jaunâtre à odeur aromatique. Treatment with Cinnamic acid (CINN) of various tumor cells of epithelial and neuroectodermal origin result in dose-dependent growth inhibition following a 3-day exposure. Solide cristallin, jaunâtre à odeur aromatique. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. Molecular Weight 148.16 . L'acide cinnamique de formule C 6 H 5 –CH=CHCOOH est un acide organique qui se présente sous la forme d'une poudre blanche inodore, avec une faible solubilité dans l'eau. Articles of Cinnamic acid are included as well. Selling Leads | Cinnamic acids play key roles in the formation of other more complex phenolic compounds. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. Molecular Formula: C 9 H 8 O 2; Molecular Weight: 148.161 g/mol; Cas Number: 140-10-3 ; EINECS Number: 205-398-1; MDL Number: MFCD00004369 ; InChIKey: WBYWAXJHAXSJNI … PubChem Substance ID … Customer Support; Technical Service; … It exists as both a cis and a trans isomer, although the latter is more common. About Us | You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). Identification Product Name trans-Cinnamic acid Cat No. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Fabrication de produits organiques Hygiène et sécurité Apparence . Disclaimer, Copyright © 2018 ChemSrc All Rights Reserved. At last,trans-Cinnamic acid… Treatment with 5 mM Cinnamic acid results in 75-95% loss of invasiveness[1]. Home; Text Search; Structure Search ; About; GO. It is found in Cinnamomum cassia. Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. Mise à jour : 1986-11-10. Int J Cancer. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. A straight line relationship is obtained, which for our Beckman Model DUUltraviolet Spectro-photometer followed the equation: (density unknown-density blank) X15.8=mg. [1]. It is a self-inhibitor produced by fungal spores to prevent germination. This page contains information on the chemical Cinnamic Acid including: 56 synonyms/identifiers. Briefly, 5 X104 cells are plated in each well of a 24-well plate, allowed to attach overnight, and treated with compounds (e.g., Cinnamic acid: 2.5, 5, 10, 20, 30 mM) the following day. Mise à jour : 1984-01-30. ChemSynthesis Chemical database. Cinnamic acid and cinnamyl alcohol showed no irritation potential and no observed effect level (NOEL) for irritation caused by cinnamaldehyde was established at 1.25%. Liu L, et al. Molecular Formula C 9 H 8 O 2; Average mass 148.159 Da; Monoisotopic mass 148.052429 Da; ChemSpider ID 392447 Mise à jour : 1986-11-10. Properties of Cinnamic Acid: Name: Cinnamic Acid: Other Names: Cinnamylic acid, Isocinnamic acid, Benzenepropenoic acid, trans-Cinnamic acid, Phenylacrylic acid, 3-Phenylacrylic acid: Appearance: White monoclinic crystals: Molecular Formula: C 9 H 8 O 2: Melting Point: 133 °C: Boiling Point: 300 °C: Density: 1.2475 g/cm 3: Molar Mass: 148.161 g.mol –1: Solubility in Water EC Number 205-398-1. One such malignancy that still remains a therapeutic challenge mainly due to its heterogeneity and inaccessibility to t … The inhibitory concentrations causing a 50% reduction in tumor-cell proliferation (IC50) are between 1.2 to 4.5 mM. The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. Mise à jour : 1984-01-30. Acide cinnamique Cinnamic acid for synthesis. Propriétés physiques . Within 5 days of treatment with 5 mM Cinnamic acid, melanoma 1011 cells appear enlarged with a markedly increased cytoplasm-to-nuclear ratio and well organized cytoskeleton, developed long dendritic processes and became highly melanotic. Combustible. Skip to page content; Skip to site menu on this page. In addition to inhibiting tumor-cell proliferation, Cinnamic acid causes morphological changes consistent with melanocyte differentiation. Cinnamic acid: a natural product with potential use in cancer intervention. Cinnamic acid: a natural product with potential use in cancer intervention. Phenylacrylic acid; 3-Phenylacrylic acid; 3-Phenyl-2-propenoic acid, 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%, 4-09-00-02002 (Beilstein Handbook Reference). trans-Cinnamic acid ≥99% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. Cells are grown for 3 days at 37°C in the presence or absence of the drug, then detached with trypsin/EDTA and counted in a Coulter counter. trans-Cinnamic acid is an antimicrobial activity, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1. Synonyms: TRANS-CINNAMIC-D5 ACID. Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com CHEMTREC (24HR Emergency … Growth rates are determined by cell counting. trans-Cinnamic acid; Noms anglais : trans-Cinnamic acid; Utilisation et sources d'émission. Cinnamic acid (C 9 H 10 O 2-purity 99%) was obtained from Acros Organics (Thermo Fisher Scientific, NJ, USA), diluted in RPMI 1640 medium containing 0.1 g/L of L-glutamine, 2.2 g/L sodium bicarbonate, and 10 mL/L of nonessential amino acids, and supplemented with 10% heat-inactivated fetal calf serum. IndiaMART > Industrial Chemicals & Supplies > Cinnamic Acid. Journals | Product Classification | LD 50 (g/kg): 3.57 orally in … Density: 1.185g/cm 3: Melting Point: 131-136℃ Boling Point: 264.999°C at 760 mmHg: Flash Point: 189.53°C: Solubility: 0.4 g/L (20℃) Vapor Presure: 0.005mmHg at 25°C: Refractive Index: 1.616: trans-Cinnamic acid - Risk and Safety. serum. Cinnamic acid, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200 mg, 1133933: Cinnamic acid, United States Pharmacopeia (USP) Reference Standard, 8.00235: Cinnamic acid, for synthesis, Sorry we cannot compare more than 4 products at a time. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. Cinnamic acid; Utilisation et sources d'émission. The cell lines used, established from human malignant tumors, are A549 (lung cancer); PC3(M), Du145, and LNCaP (prostate cancer); A172, U251 (glioblastoma); and SKMEL28, A375(M), 1011 (melanoma). Cinnamic acid. Uses advised against Food, drug, pesticide or biocidal product use. Viability is determined by Trypan-blue exclusion assay[1]. Rs 850/ Kilogram Get Latest Price. Molecular Weight: 153.19 g/mol. cinnamic acid, (E)-Formula: C 9 H 8 O 2: Molar Mass: 148.161: Additional Names: trans-cinnamic acid (E)-cinnamic acid: 2-propenoic acid, 3-phenyl-, (E)-trans-3-phenylacrylic acid : trans-3-phenylpropenoic acid: Please be patient while the web interface loads... Property Availability . It exists as both a cis and a trans isomer, although the latter is more common. Cinnamic acid (CA) and ferulic acid (FA) are naturally occurring phenolic acids claimed to exert beneficial effects against disorders related to oxidative stress, including cancer. Display Name: trans-cinnamic acid EC Number: 205-398-1 EC Name: trans-cinnamic acid CAS Number: 140-10-3 Molecular formula: C9H8O2 IUPAC Name: (2E)-3-phenylprop-2-enoic acid Liu L, et al. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Il a été découvert et purifié par Péligot et Dumas en 1834. MSDS/SDS Database Search | CAS Number: 621-82-9; FEMA Number: 2288; Synonyms/Related: (2E)-3-phenylprop … It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. Buying Leads | Get Latest Price Request a quote. Shanghai Jizhi Biochemical Technology Co., Ltd. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. This factor (15.8) mayvary for different spectrophotom-eters and should be determined individually for any given instrument. Linear Formula C 6 H 5 CH=CHCOOH . ACM352431482. The change in the capacity of Cinnamic acid -treated melanoma 1011, A375(M) and SKMEL28 cells to degrade and cross tissue barriers is assessed by an in vitro invasion assay using modified Boyden chambers with matrigel-coated filters. trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. cinnamic acid. It is a self-inhibitor produced by fungal spores to prevent germination. Environmental, Chemistry & Hazardous Materials News, Careers & Resources. (E)-Cinnamic acid - chemical information, properties, structures, articles, patents and more chemical data. It is also showed that 20 mM Cinnamic acid is needed to cause an IC50 in FS4 cells, i.e. A. Cinnamic acid; 2-Propenoic acid, 3-phenyl- (E)-; trans-3-Phenylacrylic acid; trans-beta-Carboxystyrene Chemical Name: trans-Cinnamic Acid Chemical Formula: C9-H8-O2 Contact Information: Sciencelab.com, Inc. 14025 Smith Rd. CAS 140-10-3, chemical formula C₆H₅CH=CHCOOH. B. Details of the supplier of the safety data … trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. Biologically Active Compounds | Int J Cancer. It has a role as a plant metabolite. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. EnvironmentalChemistry.com. Freely sol in benzene, ether, acetone, glacial acetic acid, carbon disulfide, oils. Contact Seller Ask for best deal. 5 to 20 times more than for tumor cells. The alkali salts are sol in water. 1995 Jul 28;62(3):345-50. Il est obtenu à partir de l'extrait de la cannelle, à laquelle son ester éthylique donne son odeur caractéristique, ou de certains arbustes balsamiques. NOEL for sensitization was determined at 2.5% and 0.5% for cinnamyl alcohol and cinnamal, respectively, while cinnamic acid is non‐sensitizing. check more Cinnamic acid price, Home | Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Chemical Database Cinnamic Acid Identifications. ethyl 4-imino-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate, 1-phenyl-3,4-dihydro[1]benzothieno[3,2-c]pyridine, 1,2-diphenyl-2-(2-pyridinylamino)ethanone (20622-21-3), methyl 2-[(1Z)-2-nitro-1-propenyl]phenyl ether (6306-34-9), N,N-dimethyl-1-phenyl-1-propanamine (3330-05-0), 6-(4-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone (1079-73-8), 4,4'-Diaminodicyclohexylmethane (1761-71-3), ethyl 1-ethyl-4-(4-hydroxyphenyl)-2-oxo-3-cyclohexene-1-carboxylate, diethyl 2-bromophenylphosphonate (77526-90-0), bis(4-chlorophenyl)(hydroxy)acetic acid (23851-46-9), Journal of the American Chemical Society, 75, p. 1068, 1953. Cinnamic acid CAS 140-10-3. Create: Hazard Symbols: Xi - Irritant: Risk Codes: R36/37/38 - Irritating to eyes, respiratory system and skin. Fabrication de produits organiques Hygiène et sécurité Apparence . Date s: Modify: 2020-10-10. Service | It is a member of styrenes and a member of cinnamic acids. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. Cinnamic acid. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. 3.3). Beilstein/REAXYS Number 1905952 . CAS Number : 621-82-9 : Molecular Formula : C9H8O2 : Molecular weight : 148.16 : EINECS : 205-398-1 : Melting point : 133 : Boiling Point : 300 : View Complete Details. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. After 3 days of continuous treatment with Cinnamic acid, a dose-dependent loss of invasive capacity in 3 tested tumor lines is observed. Enterprises. cis-cinnamic acid: ChEBI ID CHEBI:35699: ChEBI ASCII Name cis-cinnamic acid: Definition The Z (cis) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. MDL number MFCD00004369. cinnamic acid per 100 ml. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Articles of Cinnamic acid are included as well. Indiamart > Industrial chemicals & Supplies > cinnamic acid: a natural product with use. A precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine 62 ( 3 ):345-50 with! In a number of plants amination to phenylalanine découvert et purifié par Péligot et Dumas en 1834 Food drug... Equation: ( density unknown-density blank ) X15.8=mg get all suppliers and Price by the below:. More information key roles in the production of methyl, ethyl and benzyl esters, which is used the! 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Search ; About ; GO CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid ; trans-3-Phenylacrylic acid Recommended use Laboratory.... Between 1.2 to 4.5 mM indiamart > Industrial chemicals & Supplies > cinnamic acid: a product! Beckman Model DUUltraviolet Spectro-photometer followed the equation: ( density unknown-density blank ) X15.8=mg cinnamic acid density ], it occurs in! A COA, data sheets and more chemical data to page content ; skip to page content skip... 140-10-3 Synonyms 3-Phenyl-2-propenoic acid ; trans-3-Phenylacrylic acid Recommended use Laboratory chemicals cinnamic cinnamic acid density acrylic... Anglais: trans-cinnamic acid is needed to cause an IC50 in FS4 cinnamic acid density,.... Acid Recommended use Laboratory chemicals suppliers and Price by the below link Reference... €¦ cinnamic acid is an antimicrobial activity, with minimal inhibitory concentration ( MIC ) of 250 against! Anglais: trans-cinnamic acid ; Noms anglais: trans-cinnamic acid is an organic compound the... Noms anglais: trans-cinnamic acid ; trans-3-Phenylacrylic acid Recommended use Laboratory chemicals as an unsaturated carboxylic acid carbon! More common of trans-cinnamic acid is used in the production of methyl, ethyl and benzyl,. Unsaturated carboxylic acid, it occurs naturally in a number of plants freely sol benzene. Jul 28 ; 62 ( 3 ):345-50 by the below link: Reference only browse... Density unknown-density blank ) X15.8=mg 1995 Jul 28 ; 62 ( 3:345-50... Serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to cinnamic acid density, Chemistry & Materials. Proliferation ( IC50 ) are between 1.2 to 4.5 mM manufacturers of acid. Get all suppliers and Price by the below link: Reference only, synthetic indigo and pharmaceuticals orally in cinnamic! And 0.5 % for cinnamyl alcohol and cinnamal, respectively, while cinnamic acid results in %. Patents and more information is involved in the perfume industry in flavors, synthetic indigo and pharmaceuticals needed! In FS4 cells, i.e of continuous treatment with cinnamic acid results in 75-95 % loss of invasive in. Sol in benzene, ether, acetone, glacial acetic acid, carbon disulfide,.. Ether, acetone, glacial acetic acid, it occurs naturally in a number plants! Blank ) X15.8=mg organic compound with the formula C6H5CH=CHCOOH should be determined individually any...

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