Atrial fibrillation is the commonest underlying card … Etiology and pathogenesis of thromboembolism Herz. Cardiovascular System 182469 PPT. Severe atherosclerosis of the aorta has been identified as an important morphologic indicator of an increased risk for thromboembolism. SUPER FICIAL BLEEDING OR SURFACE BLEEDING, PTS ROUTINELY TREATED WITH ASA AND HEPARIN. Clipping is a handy way to collect important slides you want to go back to later. Thrombosis is a significant problem in general medicine. of blood & blood clotting - Pathophysiology of vascular tone. CRAWFORD T. Morphological aspects in the pathogenesis of atherosclerosis. Do you have PowerPoint slides to share? By Dr S Homathy. More data are needed to understand the determinants of healthy versus dysfunctional response and immune markers for protection and the severity of disease. Their relationship to naturally occurring thrombus formation in humans is unknown, but they do offer a model for studying thrombi that are spatially and temporally defined. One of the leading causes of morbidity and mortality in developed countries via MI and Stroke. Release of tPA. Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and potentially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... - Lack of sufficient oxygen (single most common cause of cellular injury) Causes ... Pernicious Anemia. a haemodynamic disorder which has serious consequences. The white thrombus, composed pre-dominantly of platelets, forms at the point of initiation of most thrombi in the smallest to the largest vessels of the body. But even nonhospitalized, ambulant patients and apparently healthy individuals may encounter this problem. Venous thromboembolism (VTE), a disease that includes deep venous thrombosis (DVT) and pulmonary embolism (PE), is associated with high mortality, morbidity, and costs. To view this presentation, you'll need to allow Flash. THROMBOSIS. 2- composed of fibrin only. It can result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity. 1- Involves only blood Thrombus formation in the left atrium and left ventricle is primarily due to stasis of blood which causes activation of the coagulation system. Arterial hypertension Ph. See our User Agreement and Privacy Policy. Thrombin in turn converts fibrinogen to fibrin. system. Suggested Citation:"THE PATHOGENESIS OF THROMBOSIS. Presentation Summary : Thrombosis and embolism . 17 Phases of Thrombolysis. Neutralising antibodies are potential correlates of protection, … Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at UCLA – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3f4967-MzFiM They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. Now customize the name of a clipboard to store your clips. Under arterial flow conditions, thrombus formation was blocked by inhibitors of P-selectin. Or use it to create really cool photo slideshows - with 2D and 3D transitions, animation, and your choice of music - that you can share with your Facebook friends or Google+ circles. By Dr S Homathy. 14 2. Accordingly, baboons treated with ticlopidine and heparin displayed a significant reduction in platelet deposition and microvascular occlusions in the ischemic basal ganglia. Thrombus formation can have one of four outcomes: propagation, embolization, dissolution, and organization and recanalization. Arterial hypertension. Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. 23 Tissue factor and P-selectin appear to both be necessary for thrombus formation and they appear to both be resident on microparticles derived from monocytes, as indicated by the presence of monocyte proteins on the microparticles. 15 3. When inferior vena cava of rabbit was replaced by 3 cm long woven Tetron® (polyethylene terephthalates) graft under bolus injection of heparin (50 U/k… presentations for free. Proc Soc Exp Biol Med. Thrombus Formation. Prof. J. Plevkova MD, PhD. An embolus may break off and travel through the deep veins towards the heart (number 3 in the figure)[20], causing a pulmonary embolism (PE). Fibrinolysis. It's FREE! In addition, the tendency of several platelet-derived factors (e.g. Pathophysiology%20of%20acute%20and%20chronic%20renal%20failure. Thrombosis And Embolism V4us 33rd PPT. Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. precipitating clot formation .  THROMBOSIS is the formation of a clotted mass of Now customize the name of a clipboard to store your clips. 16 4. Authors; Authors and affiliations; David Bergqvist; Chapter. Platelet Adhesion. Pathogenesis of Thrombosis. That's all free as well! Pathogenesis of early thrombus formation in experimental vein graft. • Obstructing blood flow through the circulatory system. such as thrombomodulin and prostacyclin enhances thrombus formation. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The first was changes in the coagulability of the blood, the second changes in the formed elements of the blood, the third changes in the circulatory blood flow andthelast changesin thevessel walls. These methods of thrombus formation are, of course, artificial and only useful for developing experimental thrombi. Propagation of a thrombus occurs towards the direction of the heart and involves the accumulation of additional platelets and fibrin. Thrombosis is the formation of a solid mass (blood clot) from the … 3- may be life-threatening. Their most obvious function is to provide a semi-permeable barrier that regulates the exchange of fluid, nutrients, gases, and waste between the blood and tissues. The PowerPoint PPT presentation: "Pathophysiology of Thrombosis" is the property of its rightful owner. Clipping is a handy way to collect important slides you want to go back to later. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. Thrombus formation (called Virchow's triad): (1) endothelial injury, (2) stasis or turbulent blood flow (3) hypercoagulability of the blood. This may promote the development of local vasospasm, which worsens coronary occlusion. Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. doi: 10.17226/20259. Pathophysiology of liver, - Title: Pathophysiology of digestion Author: User Last modified by: User Created Date: 1/7/2012 8:47:06 AM Document presentation format: (4:3), VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY. Thrombosis, the formation of a blood clot (thrombus) that tends to plug functionally normal blood vessels, is one of the major causes of death in Western societies. - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. You just clipped your first slide! - Clinical pathophysiology of the digestive system Clinical syndromes in liver injury Lack of liver disorders ... (involved in carbohydrate, fat, protein ... PATHOPHYSIOLOGY of TOBACCO-RELATED DISEASE, - pathophysiology of tobacco-related disease, Pathophysiology of acute and chronic renal failure, - Pathophysiology of acute and chronic renal failure Renata P ov, - PATHOPHYSIOLOGY OF BURNS Dr. Shiara Ortiz-Pujols Burn Fellow NC Jaycee Burn Center, Pathophysiology of digestion. and fibrin. DEFINITION THROMBOSIS is the formation of a clotted mass of blood within the cardiovascular system. 1- Involves wall of blood Thrombosis, Ulceration, and Stroke Pathogenesis Mark Fisher, MD; Annlia Paganini-Hill, PhD; Aldana Martin, HT, HTL; Michele Cosgrove, MD; James F. Toole, MD; Henry J.M. 1- Involves only blood clotting system. Looks like you’ve clipped this slide to already. D., M D. Nataliya Potikha Regulation of arterial pressure ( P) CO leads to PR and P ... - Title: Neurological Pathophysiology Author: Yu Last modified by: Yu, Min Created Date: 2/10/2004 2:52:52 PM Document presentation format: On-screen Show (4:3). A venous thrombus has essentially two components, an inner platelet rich white thrombus forming the so-called lines of Zahn surrounded by an outer red cell dense fibrin clot . - Clinical Pathophysiology Of Cardiovascular Diseases Ph. "National Research Council. A high incidence (80.3%) of thrombus formation corresponding to the site of infarction was observed. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. J Atheroscler Res. Bondarenko * GASTRIC HYPOSECRETION IS CHARACTERIZED: Reduction the quantity of gastric juice on an empty stomach and ... PATHOPHYSIOLOGY OF NERVOUS SYSTEM DISEASES, - pathophysiology of nervous system diseases*, Clinical pathophysiology of the digestive system. Platelet Aggregation. 3- mostly life saving. If so, share your PPT presentation slides online with PowerShow.com. - Increase in tissue mass that results from the excess ... Gene on chromosome 21 carries gene for amyloid protein ... May revolve around amyloid protein ... - General Principles of Pathophysiology Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... Pathophysiology of vascular tone. PPT – Pathophysiology of Thrombosis PowerPoint presentation | free to download - id: 3d624e-Y2QzZ, The Adobe Flash plugin is needed to view this content. - PATHOPHYSIOLOGY OF HEPATIC FAILURE Assoc. 1964 Feb; 115:436–438. You can change your ad preferences anytime. Thrombosis is the formation of a solid mass (blood clot) from the … See our Privacy Policy and User Agreement for details. Details on atheroscleroris-thrombosis relationship Slides 30-32. Presentation Summary : exposure of the pro-thrombogenic basement membrane just below the endothelial cells thrombosis the formed thrombus will further block the lumen of the blood 2- composed of fibrin only. These thrombi occluded the vessel lumen, were usually found proximally in the coronary arteries, and were associated with a ruptured atheromatous plaque in 90.8 per cent of cases. - VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY Blood Flow Blood vessels = arteries, veins Three tissue layers (inside to outside) Intima Epithelium + connective ... Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial. THROMBUS BLOOD CLOT  The clotted mass is called as THROMBUS. USE PRECAUTION WITH GP IIB/IIIA INHIBITORS, HIGHER RISK OF SIDE EFFECTS WITH PTS 75 YEARS OF, 50 MG VIAL WITH ONE 10 ML VIAL OF STERILE WATER, MUST BE RECONSTITUTED, THEN USED IMMEDIATELY. - Pathophysiology of digestion MD, Prof. Yu.I. If you continue browsing the site, you agree to the use of cookies on this website. 1969. The endothelial cells that line blood vessels provide an active, dynamic interface between the blood stream and the arterial wall. Pathogenesis of Atherosclerosis. Thrombus formation appears to require both tissue factor and P-selectin (17,18). SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. 1991 Dec;16(6):395-404. And, best of all, most of its cool features are free and easy to use. × R. G. Mason, Jr. Narrowing of channel leads to TURBULENCE which precipitates clot formation. And they’re ready for you to use in your PowerPoint presentations the moment you need them. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. DEFINITION ARTERIAL THROMBOSIS. They are all artistically enhanced with visually stunning color, shadow and lighting effects. How it occurs • Two components : Aggregated platelets form platelet plug Mesh of cross-linked fibrin protein When body produce excessive clotting factors like platelets and Fibrin, it forms an embolus that moves around the b - SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. 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